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最近の主な研究実績(英文論文)のご紹介

2011年

Ninomiya T
Is metabolic syndrome a risk factor for cardiovascular disease in late elderly?
Am J Hypertens 24: 1193, 2011

Arima H, Anderson C, Omae T, Woodward M, Hata J, Murakami Y, Macmahon S, Neal B, Chalmers J; PROGRESS Collaborative Group
Effects of blood pressure lowering on major vascular events among patients with isolated diastolic hypertension: the perindopril protection against recurrent stroke study (PROGRESS) trial.
Stroke 42: 2339-2341, 2011

Huxley RR, Barzi F, Lam TH, Czernichow S, Fang X, Welborn T, Shaw J, Ueshima H, Zimmet P, Jee SH, Patel JV, Caterson I, Perkovic V, Woodward M; Asia Pacific Cohort Studies Collaboration and the Obesity in Asia Collaboration (Hisayama: Kiyohara Y)
Isolated low levels of high-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease: an individual participant data meta-analysis of 23 studies in the Asia-Pacific region.
Circulation 124: 2056-2064, 2011

Matsuzaki M, Ogihara T, Umemoto S, Rakugi H, Matsuoka H, Shimada K, Abe K, Suzuki N, Eto T, Higaki J, Ito S, Kamiya A, Kikuchi K, Suzuki H, Tei C, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events Trial Group(Kiyohara Y)
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial.
J Hypertens 29: 1649-1659, 2011

Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J; Chronic Kidney Disease Prognosis Consortium( Ninomiya T)
Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts.
Kidney Int 80: 93-104, 2011

Brugts JJ, Isaacs A, de Maat MP, Boersma E, van Duijn CM, Akkerhuis KM, Uitterlinden AG, Witteman JC, Cambien F, Ceconi C, Remme W, Bertrand M, Ninomiya T, Harrap S, Chalmers J, Macmahon S, Fox K, Ferrari R, Simoons ML, Danser AJ
A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals.
J Hypertens 29: 509-519, 2011

Sugiyama H, Yokoyama H, Sato H, Saito T, Kohda Y, Nishi S, Tsuruya K, Kiyomoto H, Iida H, Sasaki T, Higuchi M, Hattori M, Oka K, Kagami S, Nagata M, Kawamura T, Honda M, Fukasawa Y, Fukatsu A, Morozumi K, Yoshikawa N, Yuzawa Y, Matsuo S, Kiyohara Y, Joh K, Taguchi T, Makino H; Committee for Standardization of Renal Pathological Diagnosis and Working Group for Renal Biopsy Database, Japanese Society of Nephrology, Tokyo, Japan(Ninomiya T)
Japan Renal Biopsy Registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan.
Clin Exp Nephrol 15: 493-503, 2011

Czernichow S, Zanchetti A, Turnbull F, Barzi F, Ninomiya T, Kengne AP, Lambers Heerspink HJ, Perkovic V, Huxley R, Arima H, Patel A, Chalmers J, Woodward M, Macmahon S, Neal B; on behalf of the Blood Pressure Lowering Treatment Trialistsʼ Collaboration
The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials.
J Hypertens 29: 4-16, 2011

Kansui Y, Ohtsubo T, Goto K, Sakata S, Ichishima K, Fukuhara M, Ohta Y, Matsumura K
Association of serum uric acid with blood pressure in Japanese men. Cross-sectional study in work-site group.
Circ J 75: 2827-2832, 2011

Doi Y, Ninomiya T, Hata J, Hirakawa Y, Mukai N, Ikeda F, Fukuhara M, Iwase M, Kiyohara Y.
N-Terminal Pro-Brain Natriuretic Peptide and Risk of Cardiovascular Events in a Japanese Community: the Hisayama Study.
Arterioscler Thromb Vasc Biol 31:2997-3003, 2011 Pubmedへのリンク

Ohara T, Doi Y, Ninomiya T, Hirakawa Y, Hata J, Iwaki T, Kanba S, Kiyohara Y.
Glucose tolerance status and risk of dementia in the community: the Hisayama Study.
Neurology 77: 1126-1134, 2011 Pubmedへのリンク

Matsuzaki T, Sasaki K, Hata J, Hirakawa Y, Fujimi K, Ninomiya T, Suzuki SO, Kanba S, Kiyohara Y, Iwaki T.
Association of Alzheimer disease pathology with abnormal lipid metabolism: the Hisayama Study.
Neurology 77: 1068-1075, 2011 Pubmedへのリンク

Arakawa S, Yasuda M, Nagata M, Ninomiya T, Hirakawa Y, Doi Y, Kiyohara Y, Ishibashi T.
Nine-year incidence and risk factors for retinal vein occlusion in a general Japanese population: the Hisayama Study.
Invest Ophthalmol Vis Sci 52: 5905-5909, 2011 Pubmedへのリンク

Ohara T, Ninomiya T, Kubo M, Hirakawa Y, Doi Y, Hata J, Iwaki T, Kanba S, Kiyohara Y.
Apolipoprotein genotype for prediction of Alzheimers disease in older Japanese: the Hisayama Study.
J Am Geriatr Soc 59: 1074-1079, 2011 Pubmedへのリンク

Yasuda M, Kiyohara Y, Wang JJ, Arakawa S, Yonemoto K, Doi Y, Ninomiya T, Ishibashi T.
High serum bilirubin levels and diabetic retinopathy: the Hisayama Study.
Ophthalmology 118: 1423-1428, 2011 Pubmedへのリンク

Ninomiya T, Ohara T, Hirakawa Y, Yoshida D, Doi Y, Hata J, Kanba S, Iwaki T, Kiyohara Y.
Midlife and late-life blood pressure and dementia in Japanese elderly: the Hisayama Study.
Hypertension 58: 22-28, 2011 Pubmedへのリンク

Usui T, Ninomiya T, Nagata M, Doi Y, Hata J, Fukuhara M, Kiyohara Y.
Albuminuria as a risk factor for peripheral arterial disease in a general population: the Hisayama Study.
J Atheroscler Thromb 18: 705-712, 2011 Pubmedへのリンク

Hata J, Doi Y, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Hirakawa Y, Kitazono T, Kiyohara Y.
Combined effects of smoking and hypercholesterolemia on the risk of stroke and coronary heart disease in Japanese: the Hisayama Study.
Cerebrovasc Dis 31: 477-484, 2011 Pubmedへのリンク

Yonemoto K, Doi Y, Hata J, Ninomiya T, Fukuhara M, Ikeda F, Mukai N, Iida M, Kiyohara Y.
Body mass index and stroke incidence in a Japanese community: the Hisayama Study.
Hypertens Res 34: 274-279, 2011 Pubmedへのリンク

Umeno J, Asano K, Matsushita T, Matsumoto T, Kiyohara Y, Iida M, Nakamura Y, Kamatani N, Kubo M.
Meta-analysis of published studies identified eight additional common susceptibility loci for Crohns disease and ulcerative colitis.
Inflamm Bowel Dis 17: 2407-2415, 2011 Pubmedへのリンク

Arakawa S, Takahashi A, Ashikawa K, Hosono N, Aoi T, Yasuda M, Oshima Y, Yoshida S, Enaida H, Tsuchihashi T, Mori K, Honda S, Negi A, Arakawa A, Kadonosono K, Kiyohara Y, Kamatani N, Nakamura Y, Ishibashi T, Kubo M.
Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
Nat Genet 43: 1001-1104, 2011 Pubmedへのリンク

Woodward M, Tsukinoki-Murakami R, Murakami Y, Suh I, Fang X, Ueshima H, Lam TH; Asia–Pacific Cohort Studies Collaboration(Kiyohara Y).
The epidemiology of stroke amongst women in the Asia-Pacific region.
Womens Health 7: 305-317, 2011 Pubmedへのリンク

Emerging Risk Factors Collaboration, Wormser D, Kaptoge S, Di Angelantonio E, Wood AM, Pennells L, Thompson A, Sarwar N, Kizer JR, Lawlor DA, Nordestgaard BG, Ridker P, Salomaa V, Stevens J, Woodward M, Sattar N, Collins R, Thompson SG, Whitlock G, Danesh J.(Kiyohara Y, Arima H, Doi Y, Ninomiya T)
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies.
Lancet 377: 1085-1095, 2011 Pubmedへのリンク

Emerging Risk Factors Collaboration, Seshasai SR, Kaptoge S, Thompson A, Di Angelantonio E, Gao P, Sarwar N, Whincup PH, Mukamal KJ, Gillum RF, Holme I, Njølstad I, Fletcher A, Nilsson P, Lewington S, Collins R, Gudnason V, Thompson SG, Sattar N, Selvin E, Hu FB, Danesh J.(Kiyohara Y)
Diabetes mellitus, fasting glucose, and risk of cause-specific death.
N Engl J Med  364: 829-841,2011 Pubmedへのリンク

Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index).(Kiyohara Y)
National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants.
Lancet 377: 557-567, 2011 Pubmedへのリンク

Sakane N, Sato J, Tsushita K, Tsujii S, Kotani K, Tsuzaki K, Tominaga M, Kawazu S, Sato Y, Usui T, Kamae I, Yoshida T, Kiyohara Y, Sato S, Kuzuya H; Japan Diabetes Prevention Program (JDPP) Research Group.
Prevention of type 2 diabetes in a primary healthcare setting: three-year results of lifestyle intervention in Japanese subjects with impaired glucose tolerance.
BMC Public Health 11: 40, 2011 Pubmedへのリンク

Kadota A, Miura K, Okamura T, Hozawa A, Murakami Y, Fujiyoshi A, Takashima N, Hayakawa T, Kita Y, Okayama A, Nakamura Y, Ueshima H; NIPPON DATA90 Research Group.(Kiyohara Y)
Relationship of moderate metabolic risk factor clustering to cardiovascular disease mortality in non-lean Japanese: a 15-year follow-up of NIPPON DATA90.
Atherosclerosis 215: 209-213, 2011 Pubmedへのリンク

Murakami Y, Miura K, Okamura T, Ueshima H; EPOCH-JAPAN Research Group.(Kiyohara Y)
Population attributable numbers and fractions of deaths due to smoking: a pooled analysis of 180,000 Japanese.
Prev Med 52: 60-65, 2011 Pubmedへのリンク

Shimazaki Y, Akifusa S, Takeshita T, Shibata Y, Doi Y, Hata J, Ninomiya T, Hirakawa Y, Kiyohara Y, Yamashita Y.
Effectiveness of the salivary occult blood test as a screening method for periodontal status.
J Periodontol 82: 581-587, 2011 Pubmedへのリンク

Lam EK, Batty GD, Huxley RR, Martiniuk AL, Barzi F, Lam TH, Lawes CM, Giles GG, Welborn T, Ueshima H, Tamakoshi A, Woo J, Kim HC, Fang X, Czernichow S, Woodward M.
Asia Pacific Cohort Studies Collaboration.(Kiyohara Y, Arima H, Iida M) Associations of diabetes mellitus with site-specific cancer mortality in the Asia-Pacific region.
Ann Oncol 22: 730-738, 2011 Pubmedへのリンク

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